David Davis MP has urged the House of Lords to pass the bill to trigger Article 50 after it cleared its final hurdle in the House of Commons last night.
The European Union (Notification of Withdrawal) Bill passed by an overwhelming majority in the Commons, with the Government fending off attempts to amend the bill.
It now needs to be approved by peers in the House of Lords before receiving royal assent to become an act and allowing Theresa May to trigger Article 50.
The Brexit Secretary warned the Lords not to try to change the bill, or risk facing "dire recriminations."
He told Sky News: "The simple thing is the Lords is a very important institution.
"I expect it to do its job and patriotic duty to give us the right to go on and negotiate the new relationship with the EU.
One controversial aspect of the bill was that it passed through unamended, despite attempts to ensure the rights of EU nationals. In response, the Government has said it will treat EU nationals' status as priority in Brexit negotiations as soon as possible.