The NHS in England is spending more than £11 billion a year on illnesses related to poor diet, smoking and drinking, according to officials.
Public Health England has warned that conditions such as diabetes and smoking-related bronchitis have become an untreatable epidemic.
Unless the problems are tackled effectively, the NHS will become unaffordable.
The experts have also warned the problem is worse in areas of poverty and high unemployment, and can lead to serious health problems such as cancer, type 2 diabetes, lung and heart disease.
However, some areas are trying to tackle the problem head on. For example in Fleetwood, Lancashire a project will take place over the next year to help people change their behaviour.
The project includes educating children in primary school, working with local sports clubs and having more green spaces.
Health experts say all areas of the country must face up to the challenge to combat this problem.