Harvey Weinstein has been charged with rape following an investigation by police in New York.
The film producer was arrested on Friday morning in his first public appearance since October before being charged with rape, a criminal sex act, sex abuse and sexual misconduct for incidents involving two separate women.
He has been the subject of an investigation in the US into allegations.
A statement from the New York Police Department confirmed the charges and thanked "these brave survivors for their courage to come forward and seek justice".
The arrest and charges follow the joint investigation between the NYPD and the Manhattan District Attorney's office.
In his first public appearance since October, Weinstein arrived at the New York Police Department's 1st Precinct wearing a black suit, white shirt and blue jumper.
A police official previously said Weinstein will be charged with committing a criminal sex act after an aspiring actress alleged he forced her to perform oral sex in 2004.
It relates to a woman who has not been identified or spoken publicly, the official said.
Weinstein - whose lawyers have denied allegations he forced himself on women - said nothing as he entered the police precinct.
He was clutching two books, Something Wonderful: Rodgers And Hammerstein's Broadway Revolution, by Todd S Purdum, and Richard Schickel's biography of producer, director and writer Elia Kazan.
He has been arraigned on the charges.
The New York Times reported on Thursday that investigators in Manhattan were preparing to arrest the disgraced movie mogul and he was expected to surrender to authorities.
Ais attorney Benjamin Brafman said: "Mr. Weinstein has always maintained that he has never engaged in non-consensual sexual behavior with anyone.
"Nothing about today's proceedings changes Mr. Weinstein's position. He has entered a plea of not guilty and fully expects to be exonerated."