A man has been detained in connection with 12 suspicious packages sent to senior politicians and officials including Former US President Barack Obama and Hillary Clinton.
Law enforcement officials have identified the man as 56-year-old Cesar Sayoc from Florida.
Earlier on Friday, authorities said suspicious packages addressed to New Jersey senator Cory Booker and former National Intelligence director James Clapper had been intercepted.
They added that both packages were similar to those containing pipe bombs sent to other prominent critics of US President Donald Trump.
Footage from television news helicopters showed federal agents surrounding a white van in a car park in Plantation, Florida.
The van had several stickers in the windows, including American flags and Mr Trump.
The packages also targeted ex-vice president Joe Biden and former attorney general Eric Holder.
Packed with powder and broken glass
President Trump said the suspect will be prosecuted to the “fullest extent of the law”.
Earlier this week, the CNN office was evacuated after another package was found inside their building, addressed to former CIA director John Brennan.
The devices contained timers and batteries, but were not rigged to explode on opening, said law enforcement officials.
They added they were uncertain whether the devices were poorly designed or never intended to cause physical harm.
- Read more: Counter terrorism specialist blames Donald Trump for spate of pipe bombs sent to prominent US politicians
The president claimed he was being blamed for the packages, saying in a tweet: "Funny how lowly rated CNN, and others, can criticize me at will, even blaming me for the current spate of Bombs and ridiculously comparing this to September 11th and the Oklahoma City bombing, yet when I criticize them they go wild and scream, 'it's just not Presidential!'"
The bombs, which were packaged in manila envelopes, were about six inches long and packed with powder and broken glass, according to an official who viewed the x-ray images.
The devices were made from PVC pipe and covered with black tape, said officials.
The first package was discovered on Monday after being sent to the billionaire George Soros, a major donator to the Democratic Party.