Melania Trump has said she loves her husband and has "much more important things to think about" than allegations he cheated on her.
Mrs Trump, who was interviewed by US TV network ABC while touring Africa last week, said people are just spreading rumours about her marriage.
"I know people like to speculate and media like to speculate about our marriage and circulate the gossip," she said. "But I understand the gossip sells newspapers, magazines ... and, unfortunately, we live in this kind of world today."
She insisted allegations of her husband US President Donald Trump's infidelities are not a concern.
Mr Trump, who during the 2016 presidential campaign was heard on tape talking about groping and trying to have sex with women, has been accused of having multiple affairs.
Porn star Stormy Daniels and ex-Playboy Playmate Karen McDougal have said they had sex with him years ago.
'We are fine'
Mr Trump has denied the trysts with Ms Daniels and Ms McDougal but has acknowledged reimbursing his lawyer for a 130,000 US dollar hush money payment made to Ms Daniels. Mrs Trump has generally kept quiet on the subject.
Asked in the interview if she loves her husband, Mrs Trump said: "Yes, we are fine. Yes."
She played down a suggestion the repeated rumours of his philandering had put a strain on their marriage.
"It is not a concern and focus of mine," she said. "I'm a mother and a first lady, and I have much more important things to think about and to do."
'I know what is true'
But when she was asked if the repeated rumours had hurt her, she paused. Then she reiterated the "media world is speculating".
"Yeah, it's not always pleasant, of course," she said. "But I know what is right and what is wrong and what is true and not true."
Other portions of the interview aired earlier this week featured Mrs Trump saying she could be "the most bullied person" in the world and saying women who make accusations of sexual assault need to "show the evidence".
Mr Trump's former personal lawyer Michael Cohen pleaded guilty in August to campaign finance violations alleging he, Mr Trump and the National Enquirer tabloid were involved in buying the silence of Ms Daniels and Ms McDougal after they alleged affairs with Mr Trump.