More than one third of people surveyed in Wales have said they would support the country becoming independent if it meant staying in the European Union.
The YouGov poll, commissioned by Plaid Cymru, found that 33 per cent of just over 1,039 Welsh adults would back breaking away from the UK.
Plaid Cymru leader Adam Price said the new poll represented a "historic high" for hopes of an independent Wales.
"Westminster is in turmoil. Boris Johnson's reckless Tory government and Jeremy Corbyn's chaotic so-called opposition are wrecking Wales's future," he said.
"It is no wonder that we are witnessing a surge in support for a New Wales - a nation proudly taking its place as an equal partner on the international stage."
However, only 24 per cent of those surveyed said that they would vote in favour of Welsh independence if a referendum was held tomorrow, with 48 per cent saying they would vote against independence at this time.
Growing support for autonomy has led to a series of rallies recently held in Cardiff, Caernarfon and Merthyr Tydfil, where thousands joined marches organised by the pro-independence group, All Under One Banner Cymru.
Over 3,000 attended the first march in Cardiff, and the event in Caernarfon saw 10,000 attendees, which is almost double the population of the town.